TCRT-PGEN Fundamental & Technical Discussion Board - From a poster on the other board - Views? - TCRT-PGEN Fundamental & Technical Discussion Board - InvestorVillage


TCRT-PGEN Fundamental & Technical Discussion Board
This is a semi-private group. You are free to browse messages, but you must be a member of this group to post messages. Join This Group

Group: TCRT-PGEN Fundamental & Technical Discussion Board   /  Message Board  /  Read Message

 
 






Keyword
Subject
Between
and
Rec'd By
Authored By
Minimum Recs
  
Previous Message  Next Message    Post Message    Post a Reply return to message boardtop of board
Msg  32363 of 33089  at  1/30/2023 9:42:08 PM  by

redplate


 In response to msg 32361 by  Frank303
view thread

Re: From a poster on the other board - Views?

I hate to be the one bringing bad news but that 17% may be worse than it looks. Those tumors that have lost a single HLA allele (lost heterozygosity) are most commonly found in patients that had generated effective CTL responses and these tumors are the ‘escape’ mutations (down regulation/methylation of upstream elements. This emphasizes the ability of large volume tumors to generate escape from immune pressure. So as partial responses are seen this ‘escape pathway’ has to be carefully examined. Veru high dose killing early and fast may be required to kill before escape occurs.


     e-mail to a friend      printer-friendly     add to library      
|  
Recs: 6  
   Views: 0 []
Previous Message  Next Message    Post Message    Post a Reply return to message boardtop of board

Replies
Msg # Subject Author Recs Date Posted
32366 Re: From a poster on the other board - Views? dachmeister4u 8 1/31/2023 10:19:52 AM




Financial Market Data provided by
.
Loading...